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duke knooby 04 Jan 2021 23:13

I was interested to read this morning in an article titled Oxford vaccine regulatory authorisation: FAQ

"This efficacy result is based on data from younger (18–55 years old) adults – how do you know that it is safe for older adults?

The MHRA have approved this vaccine and have come to the conclusion that the dosing schedule can remain the same for these groups, we know further results are due in the next couple of months and will build on existing knowledge for older adults."

Link for the above..

https://www.research.ox.ac.uk/Articl...regulatory-faq


Which had me wondering what have the MHRA published about this?

So a quick visit to the government website revealed the following...

"Elderly population

Efficacy and safety data are currently limited in individuals ≥65 years of age (see sections 4.8 and 5.1). No dosage adjustment is required.
Paediatric population

The safety and efficacy of COVID-19 Vaccine AstraZeneca in children and adolescents (aged <18 years old) have not yet been established. No data are available."

and demographics quoted as...

"Baseline demographics were well balanced across COVID-19 Vaccine AstraZeneca and control treatment groups. Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 94.1% of participants were 18 to 64 years old (with 5.9% aged 65 or older); 60.7% of subjects were female; 82.8% were White, 4.6% were Asian, and 4.4% were Black. A total of 2,070 (35.6%) participants had at least one pre-existing comorbidity (defined as a BMI ≥30 kg/m2, cardiovascular disorder, respiratory disease or diabetes). The median follow-up time post-dose 1 and post-dose 2 was 132 days and 63 days, respectively."

Full link to the above information...

https://www.gov.uk/government/public...ne-astrazeneca

And yet the government is rolling this out first to the elderly and vulnerable?

Seems to me, this roll out is going to be the largest, virtually untested drug trial in the history of the UK

duke knooby 04 Jan 2021 23:21

And three more things...

1, I'm glad I decided to just copy and paste most of the above, or I'd still be typing it out in an hours time.

2, Whomever typed/published the Oxford FAQ above should've used a computer with a working space key.

3, More lock down lunacy for all. :evil:

duke knooby 08 Jan 2021 01:00

I only found the Northern Ireland daily, and cumulative Covid-19 stats today.

And page 4, the Covid-19 Testing Overview really concerns me.

It very kindly releases separate pillar 1, pillar 2 and finally combined test statistics

And the positive test rate for pillar 2 is Considerably, Exponentially higher than for pillar 1 tests.

I might actually (for the first time ever) have to write to an MP to seek some answers.

duke knooby 17 Jan 2021 21:41

That's been 72 hours without alcohol, and over a weekend too.

Long time since I did that.

tonyloaf 21 Jan 2021 20:27

Keep rocking everyone!!

duke knooby 05 Feb 2021 23:00

I couldn't believe the total deaths registered chart (for England and Wales) when I looked at it today... There has been a massive spike in deaths recorded in England and Wales this last few weeks. The jump on the chart was so big, I didn't believe it, and looked up the figures myself on the ONS. Between beginning of September and 1st of January the total weekly deaths recorded in England and Wales have fluctuated between 8k to 13k per week...

December to January figures

04/12/20 12,303
11/12/20 12,292
18/12/20 13,011
25/12/20 11,520
01/01/21 10,069

And then the total death rate goes nuts

08/01/21 17,751
15/01/21 18,042
22/01/01 18,676

Data sources..
https://www.ons.gov.uk/peoplepopulat...nglandandwales

What has caused the massive spike in deaths?
Why is it affecting the elderly more in January than December?
And why haven't the media investigated?

duke knooby 10 Feb 2021 17:44

I wonder will the vaccines end up killing more people than the virus did.

Lee B 11 Feb 2021 16:57

Quote:

Originally Posted by duke knooby (Post 624472)
I wonder will the vaccines end up killing more people than the virus did.

Happy to put your mind at rest; no, they won't.

duke knooby 28 Feb 2021 01:23

I'm gonna count that as 6 weeks booze free

duke knooby 28 Feb 2021 01:27

We've pretty much got to the end of the tractor negotiations, so it's either gonna happen in the next couple of weeks, or never..

Another reason to apply old school drinking and thinking methods

duke knooby 28 Feb 2021 01:34

And I'm off the opinion, if you're at virtually no risk of dying from covid 19, the vaccines will be effective, if you're in an at risk category, probably best to hold off.

GenoJLaw 07 Mar 2021 03:13

Folk Cover of Bat Out of Hell
 
This popped up in my YouTube feed. I found it fun and Interesting
YouTube Video
https://youtu.be/WPLnh_0SU50

Evil One 10 Mar 2021 11:14

Quote:

Originally Posted by duke knooby (Post 624482)
And I'm off the opinion, if you're at virtually no risk of dying from covid 19, the vaccines will be effective, if you're in an at risk category, probably best to hold off.

I'm of the opinion that your opinion is ridiculous

duke knooby 10 Jun 2021 22:59

Quote:

Originally Posted by duke knooby (Post 624481)
We've pretty much got to the end of the tractor negotiations, so it's either gonna happen in the next couple of weeks, or never..

Took more than a couple of weeks, but it's done.

I now own a tractor.

(can't wait till my uncle gets to see it again, in person for the first time in over 30 years)

:D

madagascar 11 Jun 2021 00:03

Finally!! :)

duke knooby 25 Jul 2021 18:18

That’s been over 6 months virtually booze free, I’ve impressed myself!

And the tractor story is getting more and more into the realms of what’s the chances of that...

Firstly, finding it

Secondly, lady at the dealership still working there, and able to confirm it as the one supplied to my uncle.

Thirdly, The former training manager at the factory, who had to reconcile details of over 600 tractors at the time of the factory closure, has details of only one tractor the same model as mine... and it’s my one.

Fourthly and finally, I bought a panel on eBay, which when I contacted the seller about sourcing other panels, turns out he used to work at the dealership that supplied my tractor, and he even remembered it.

It’s almost as if it was destiny!

Guy 29 Oct 2021 08:26

Picked a good day to be filling a skip when its chucking down with rain. 🙄

Guy 30 Oct 2021 20:57

Skip filled.
With water 🤣

Guy 31 Oct 2021 00:54

Watching Meat with Philamonic Orchestra in Melbourne. If thats you with your arms in the arm during FCOl. I slaute you sir. #passion. 🤟

duke knooby 08 Nov 2021 23:38

Quote:

Originally Posted by Guy (Post 624998)
Watching Meat with Philamonic Orchestra in Melbourne. If thats you with your arms in the arm during FCOl. I slaute you sir. #passion. 🤟

were you on the booze?

duke knooby 14 Nov 2021 00:41

I can't spell anymore, and my handwriting is getting worse.

But on the bright side, I've placed my first large tractor parts order.

Lots of new bits on the way.

Guy 14 Nov 2021 09:11

Postmans gonna struggle getting those bits thru the letterbox Duke

duke knooby 14 Nov 2021 22:37

Uh huh, I dread to think how its all gonna arrive. Might have a pallet lying on the road till I get home lol

A set of mudguards will need a big box, never mind the other bits

duke knooby 03 Dec 2021 00:08

mandatory experimental jabs in parts of europe???

These are very dangerous times indeed!!

(and not due to the not particularly deadly virus)

RSG 03 Dec 2021 04:30

Meat Loaf Vh1 storytellers on videocassette.. didn't know that was even a thing.


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